Summary:

This novel is narrated by Katie Carr, who very much wants to be a good person.  She is a physician and a mother of two, and lives with her petulant husband, David.  David is the author of a column in the local newspaper called "Angriest Man in Holloway".  As their marriage falls apart, David undergoes a conversion at the hands of GoodNews, a young guru, and ceases to be sarcastic and angry, embarking instead on an effort to improve the world with acts of kindness.  Katie is forced to consider what it means to be a good person and how that affects whether to salvage her marriage, how to raise her children and how to be the type of physician she always considered herself to be.

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Except for her canary and cat, Martha (Sheila Florance) lives alone in an apartment containing fragments and memorabilia of the past which speak to a rich and complex life comprised of various relationships and wartime horrors. Many of the fragments are further referenced in flashback scenes. Three current relationships--with her caretaker, her son, and her dependent and declining neighbor, Billy (Norman Kaye)--are central to this moment in time and provide an illuminating portrayal of Martha’s struggle for independence and undiminished zest for life. While her kind caretaker, Anna (Gosia Dobrowolska), respects the old woman’s fierce need for autonomy, her son, concerned about her frailty and safety, is intent on relocation to a nursing home where she can be supervised. Martha, on the other hand, provides gentle and kind care for Billy, who has been abandoned by his family; during the night, when he is unable to find the bathroom, Martha provides gentle and unobtrusive assistance. Martha’s strength comes from character and spirit, remarkable traits which leave an indelible impression about our tendencies to conventionalize aging.

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In 1996, at the age of 31, David Biro is preparing for his specialty examinations in dermatology and is set to share a practice with his father. But he develops a visual disturbance. After repeated testing, he is found to have the rare blood disorder of paroxysmal nocturnal hemoglobinuria. The diagnosis was problematic, but the treatment choices are overwhelming. His youngest sister is a suitable donor, and he opts for a bone marrow transplant. He realizes that his decision was influenced not only by the diagnosis, but also by his personality and his reaction to the physicians.

Advance preparations are hectic and sometimes comic, especially his deposits at a local sperm bank. The pain of the transplant and the six weeks imprisonment in a small hospital room are told in graphic detail. The athletically inclined doctor suffers many complications: exquisitely painful ulcers of the scrotum, mouth, and esophagus; inflammation of the liver; unexplained fever; drug-induced delirium; weakness and weight loss.

His parents, sisters and friends leap into action to provide round-the-clock presence, but his independent wife, Daniella, resents the invasion. While David’s body is wracked with drugs and radiation, his family and his marriage are subjected to destructive forces too. Yet all--body, family, and marriage--emerge intact, though changed, by their experience.

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Most of the film takes place inside the body of a slob, a widower named Frank (Bill Murray). The live-action sequences trace Frank’s illness: because of his unhealthy habits, he contracts a virus, develops an extremely high fever, and almost dies. After a miraculous recovery, he decides to follow the advice of his sensible daughter, Shane, and get more exercise, eat healthy food, and so on.

The rest of the film is animated, and tells the story of the illness from inside Frank’s body, a city with its own police force (the immune system, its precincts in the lymph nodes), organized crime (microbes who have a steambath in Frank’s armpit), the media (NNN, the Nerve Network News). The town is run from Cerebellum Hall by the corrupt Mayor Phlegmming, who discourages healthy eating habits because the huge number of fat cells vote for him. Chaos threatens with the arrival of Thrax (the voice of Laurence Fishburne), a virus who, as he puts it himself, "makes ebola look like dandruff."

The heroes are Osmosis Jones, a white blood cell (who is literally blue, and voiced by the black comedian Chris Rock), and Drix, a cold capsule (voice of David Hyde Pierce). Jones has been suspended for using "unnecessary force," by making Frank throw up in public (and in fact saving his life by expelling a toxic oyster), and Drix develops an inferiority complex when he realizes that he does not cure disease, but is only "for the temporary relief of symptoms." The two team up as vigilantes and, along with the attractive Leah, another immune cell who works as the Mayor’s Aid, they defeat Thrax and save the city.

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Editor Chip Spann created this anthology as part of his Ph.D. dissertation in creative writing. The poems were selected because Spann hopes they "can be a comfort to the sick and a rabble-rouser for those who work at getting well" (5). The book’s 234 poems have been organized into seven sections, each section named with a phrase from one of the poems contained therein. Each section is prefaced by an introduction that focuses on Spann’s own journey from a difficult childhood and unanchored young adulthood to his current life in which he is able to combine a love of reading and writing poetry with his background of working with patients in a variety of settings -- he leads a writing group of patients, caregivers, and health professionals at Sutter Medical Center in Sacramento, California.

The seven sections concern: the body; illness and life’s journey as quest; "feelings that are screaming to get out"; looking inward at dark truths; reflecting on "early wounds"; finding creative inspiration from unexpected and small things; and "perspectives on death and aging." I counted approximately 80 poets who are represented in this anthology; those with the greatest representation (number of poems) are Raymond Carver, Lucille Clifton, Emily Dickinson, Grace Paley, Muriel Rukeyser, Mowlana Jalaluddin Rumi, May Sarton, William Stafford, and May Swenson.

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The author selected 48 works of art, famous and obscure, which are presented in chronological order as full-page color plates. On the facing page of each piece is a brief essay which includes information such as artist, date and current location of the work. The essays, as well as the introduction by the author, are insightful, well-written, and demonstrate the author’s vast knowledge as a medical historian. Selections include the "Oath of Hippocrates", Studies of the Fetus by da Vinci, The Anatomy Lesson of Nicolaes Tulp by Rembrandt, The Dwarf Sebastian de Morra by Velazquez, "Muscle-Man from Vesalius" by van Calcar, and First Operation Under Ether by Hinckley (see art annotation in this database).

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A poem in a patient’s voice. He brings "a minor issue" to the doctor’s attention, something so trivial he ought not mention it. The doctor sees so many more important problems, like John Butler who "had a terrible / case of prostate cancer." He went downhill so quickly, unlike the patient’s mother who "died of old age / the way it should be, just pooped out . . . . " She didn’t have "the big C." In any case, the patient’s problem "probably / isn’t much of anything. Don’t you agree?"

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This collection of poetry evolves from one woman’s experience with the discovery of a lump in her breast, the removal of the breast, the assault of follow-up treatment and its impact on her sense of self as well as the relationship with her husband and her environment. The poems are brief, pointed, and deeply reflective of the author’s relationship with her surroundings and her history.

Among the issues the poems most effectively address is that of loss: "I dream of losing / my car, my purse, my period" (from "On First Learning of the Lump"); and "The world’s not keeping things safe / The world’s taking away what I want" (from "What I Want"); and "You believed your dead body / would have all its fingers / all its knowledge" (from "Apologia").

The author also speaks to the importance of breasts ("Terrain") as an integral part of who she is, and the memories of times past in which she was whole as one with nature ("Bird Feeder," "Pine Forest," "Peonies").

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The New Medicine and the Old Ethics, in Albert Jonsen’s own words, is a "secular aggadah." Jonsen explains that one Talmud reviewer defined aggadah as "a magical rabbinic mode of thought in which myth, theology, poetry and superstition robustly mingle" (4). The book begins with a personal essay entitled "Watching the Doctor." Jonsen establishes his premise that the moral history of Western medicine is best understood as a paradox between altruism and self-interest, a paradox alive and well entering the 21st Century.

He then takes the reader on his "secular aggadah," blending history, myths, and stories that trace important moral developments in the practice of Western medicine. In "Askelepios as Intensivist," we learn of the early Greek values of competence in shaping medical practice. Through the influence of the Church in the medieval period, Western medicine incorporates the value of compassion through the Biblical Good Samaritan, struggles with problems of justice in the care of the poor, and further elaborates the meaning of benefit.

In "The Nobility of Medicine," Jonsen describes the contribution of Sir William Osler and other knighted medical men of the 19th Century who established the ethics of noblesse oblige in the medical profession. He traces this noble tradition to the medieval Knights Hopitallers of Saint John of Jerusalem, a group of religious who provided hostels for pilgrims to the Holy Land and cared for the sick. With essays on John Locke and Jeremy Bentham, Jonsen brings us to the 20th Century and the play of individual rights and utilitarian values in the moral life of Western medicine.

In the final essays, Jonsen describes the mingling of these traditions as a means to establish a moral frame for Western medicine in our current times where technology and science have achieved and threatened so much. Ethics, he argues, "is disciplined reflection on ambiguity" (130). In the last essay, "Humanities Are the Hormones," Jonsen brings his "secular aggadah" full circle.

He argues that the paradox of altruism and self-interest that runs through the moral history of Western medicine must continually be vitalized and examined through the Humanities. The Humanities are "the chemical messengers that course through the complicated institution of medicine and enable it to respond to the constantly changing scientific, technological, social, and economic environment" (147).

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After working with the Parisian physiologist, François Magendie, Dr. John Leggate returns to England to practice in the town of Middlethorpe in the late 1840s. He is obsessed with making a research discovery that will help humanity and establish his name. He falls in love with the intelligent and gifted Marian Brooks who aspires to a career as a concert pianist after study in Leipzig with Felix Mendelsohn. They marry and find happiness at first, but she is troubled by discovery of his past affair in France, and he is troubled by her abandoning music simply to be the type of wife he never wanted.

Leggate has a theory about the origins of cholera, but his painstaking work shows him two things: 1. his original idea is mistaken, and 2. the disease is spread by water. He does not publish, though he announces his intentions to do so. Intimidated by skeptical colleagues, he is unable to write, and the problem is exacerbated by a newspapermen who makes unwarranted accusations because he holds a grudge against Leggate’s wife.

Marian wants to help him, but he rejects her offers and retreats into himself. Their marriage is threatened. Just as cholera returns and the town learns from Leggate’s insights, John Snow publishes his famous observations on cholera. Leggate is scooped. He and Marian migrate to Canada where he is accepted for his skills and desire to be of service and she establishes a conservatory of music. Their marriage is restored.

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