Summary:

Henry Moss is a medical geneticist specializing in Hickman syndrome, a fictitious disease resembling progeria. Children with Hickman syndrome experience premature aging and invariably die before the age of twenty. The physician meets Thomas Benhamouda, a teenager who genetically has Hickman syndrome but astonishingly has no physical manifestations of the disease. Dr. Moss identifies a protein that "corrects" Hickman syndrome in the blood of Thomas and proceeds to synthesize it.

Dr. Moss violates medical ethics by administering the experimental enzyme to his favorite Hickman patient, William Durbin, a dying 14-year-old boy. It is a last-ditch effort to save William's life even though the substance has not been tested for safety or efficacy in human beings. Dr. Moss also injects himself with the enzyme. He realizes the tremendous potential the drug has not only in curing Hickman syndrome but also in extending longevity in normal individuals. He is well aware of the great financial rewards he might reap from his discovery.

After a series of injections, William's deteriorating health stabilizes and even improves but he dies in his home. Dr. Moss has failed to save the doomed boy but in the process of breaking the rules and risking his career has learned how to understand and appreciate his own life as well as reconnect with his family.

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When Dan Shapiro was 20 years old and a junior in college, he was diagnosed with "nodular sclerosing Hodgkin's disease." Thus began a five-year ordeal of chemotherapy, radiation treatments, and a bone marrow transplant that failed. But this memoir, which recounts diagnosis, treatment, and two relapses, is more than a narrative of illness. Woven in and out of the subjective experience of physical and emotional trauma is the author's life as an adolescent, a family member, a young man who falls in love with the woman who eventually becomes his wife, a graduate student learning to be a clinical psychologist.

Sequences of ordinary life are carefully juxtaposed with sections on illness and treatment, emphasizing the author's determination to incorporate his illness into his life, all part of one continuous fabric. Even though disease was enormously disruptive, "[l]ife doesn't stop when something horrible happens" (158). Part of that life was a mother who decided to grow marijuana plants in her backyard ("Mom's Marijuana") so that her son would have an antidote for the terrible nausea that accompanied his chemotherapy. It is Mom who learns in a waiting room conversation that it might be advisable for Dan to bank his sperm for the future-- and who then proceeds to make the arrangements. As the memoir ends, Dan's mother finally disposes of the dry marijuana leaves that have been hanging in her attic for several years.

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In a bleak setting, at an ocean's edge, a family grouping of three poor people, barefoot, huddled and shivering, are lost in contemplation. The figures' proportions are elongated. Imposing in their size, they take up the entire canvas. Rendered entirely in shades of blue, all other details are eliminated from the composition adding to the mood of blue empty coldness of sand, sky, and sea.

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St. Luke’s Hospital was founded in 1750 to provide free care to the impoverished mentally ill. It mixed benevolence with "unconscious cruelty" in the treatments used by the "practitioners of old," from restraints and drugs to swings and a key to force-feed recalcitrant patients. Dickens describes this gloomy edifice as he saw it on December 26, 1851, although he notes a "seasonable garniture" of holly.

The inhabitants of St. Luke’s largely sit in solitude. Dickens decries the absence of "domestic articles to occupy . . . the mind" in one gallery holding several silent, melancholy women, and praises the comfortable furnishings--and the relative "earnestness and diligence" of the inmates--in another. He uses statistics to show the prevalence of female patients, "the general efficacy of the treatment" at St. Luke’s, and the unhealthy weight gain of the inhabitants due to inactivity. Dickens describes the behavior of various distinctive inhabitants during the usual fortnightly dance, the viewing of a Christmas tree, and the distribution of presents.

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This tightly researched documentary opens with the tragic auto accident in which Ms. Kowalski is rendered comatose. During the early period of her prolonged hospitalization, tensions arise between Kowalski's domestic partner and the patient's parents, leading to a highly contentious battle for the rights not only to visit, but also to assume long term care responsibilities. As the patient regains consciousness and limited physical and cognitive skills, the drama moves from the hospital and nursing care facility to the courtroom.

For ten years, the battle for custody and the ultimate care of Ms. Kowalski rages. Drawing on trial transcripts, medical records, newspaper archives, and personal interviews, Casey Charles's work brings to life emotions and personalities that dominated the courtroom dramas and illuminates the highly contested judgments emerging from supposedly objective authorities in journalism, medicine, and the law.

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This is psychiatrist Ron Charach's seventh collection of poems. It begins with the narrator going through security in order to board an airplane--a metaphor for contemporary society: we structure more and more "security" into our lives, but the uncertainty seems to increase, rather than decrease. The theme of the book is safe passage: our attempts to achieve it, our failures, and our companions along the way. In the last poem ("The Night After"), Charach tells us, "all the talk in the world cannot dampen my fear / of a world bereft of holiness." The quest is unsuccessful, yet somehow saved by a few fleeting moments of contact with something else; perhaps, it is the sacred.

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In 1822, a young Canadian paddler named Guillaume Roleau is near death after suffering a gunshot wound to the stomach. His recovery is dramatic and scientifically important. The injury has resulted in a traumatic fistula--a porthole between the outside world and Guillaume's abdominal cavity and organs. The treating physician, Dr. William Barber, immediately recognizes the incredible opportunity for medical research and conducts a lengthy series of experiments on the process of human digestion.

Guillaume--patient, research subject, and guest in the doctor's cabin--is rowdy and frequently uncooperative. He continues to participate in the grisly experiments at least partially out of affection for the physician's wife, Julia, who helps nurse him back to health as well as providing emotional sustenance.

Julia ultimately makes a large, uncredited contribution to Dr. Barber's research. At her husband's request, she has sexual relations with Guillaume so that the unreliable man will remain with the doctor until the experiments are all completed. The efforts of this tragic trio result in a landmark textbook on gastrointestinal physiology authored by Dr. Barber and Julia's illegitimate son, Jacob, sired by Guillaume Roleau.

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In the first of this poem's three stanzas, the narrator is looking out the window, presumably on or near his fiftieth birthday. He watches as a baby possum is snatched up by a fox while the possum's mother stands dumbly by. Seeing this, the narrator notes that it is one more thing he "couldn't do anything about." In fact, he sees the drama dispassionately. He says that instead of "feeling very much" he had the sense of "something dull / like a small door being shut, / a door to someone else's house."

In the next stanza, later that night, the narrator is flipping through the TV channels but stops when he is captivated by a nurse who "had a beautiful smile / while she spoke about triage and death." Again he observes death from afar as the nurse talks about her experiences in Viet Nam and how a dying soldier asked her to bend closer so he could smell her hair.

In the final stanza, the narrator's wife comes home, tired. The narrator, however, is somehow energized; he wants to talk about the possum, the fox, and the young man who "wanted one last chaste sense / of a woman." The wife wants a drink, some music, everything "normal." But the narrator, transformed by the nurse's smile, its "pretty hint of pain / the other expressions it concealed," is no longer just an observer.

He now has "something to say," something almost inexpressible about life and death, the death that he is moving closer to but was, at the poem's beginning, unable to face. The nurse's experience--her proximity to death, her ability not only to observe but to acknowledge and honor it--has somehow transformed him.

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Poet and writer Jeanne Bryner has assembled 24 short stories to give us Eclipse, a wise and tender collection that reflects her blue-collar roots in Appalachia and industrial Ohio, and also her work as a registered nurse. These stories are about real human beings, flawed and graced, who, for the most part, care for one another, whether family or stranger, with compassion and the kind of acceptance that comes from living a hard life. Bryner's writing skills move these characters beyond easy stereotype and turn their actions--their anger over the death of a loved one or the cooking of a Sunday supper--into transformative metaphors that illuminate the sorrows and joys of everyday life.

The following stories might be of particular interest to those teaching or studying literature and medicine: "Sara's Daughters," in which a woman undergoes artificial insemination and, through her thoughts and her conversations with the nurse, perfectly reveals an infertile woman's humiliation, longing, and hope; "The Jaws of Life," in which a young woman takes her Aunt Mavis to visit Uncle Webster in a nursing home and there observes the poignant interactions of the well and the dying, the young and the old, moments infused with both charity and dread.

In addition: "Turn the Radio to a Gospel Station," in which two cleaning ladies in a hospital ER observe and philosophize about what goes on around them, the deaths and near-deaths, the kindness or mutinies of nurses, the doctors' mechanical repetition of questions, the lovers hiding in the linen closet; "The Gemini Sisters," in which a group of weight-watching women meet to shed pounds and talk about life; "Foxglove Canyon," in which a registered nurse with forty year's experience relates memories of her work, her family, and how things change when a writer comes to teach the staff and the patients about poetry, "the flower you stumble across growing near the barn, a purple bloom that nobody planted."

"Red Corvette" examines the intimacy that develops between family members, particularly when one is caregiver to the other. In this story a woman comes to visit her post-op sister and remembers, while watching her sister suffer in pain, their childhood, those moments of freedom and health she yearns for her sister to regain.

"The Feel of Flannel" is about a woman who, like her mother and grandmother, has breast cancer. She refuses to participate in a research project but instead barrels ahead into her uncertain future, planning to wear her nightgown to the grocery store and tattoo her husband's name "right here when this port comes out."

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Grace Rhodes (Lisa Eichhorn) is an unmarried New York advertising executive. Around forty years old, she decides that she wants a child and has no more time to find the right man. She becomes a client of Cryogenetics Sperm Bank and conceives by donor insemination.

As soon as she is pregnant, she becomes obsessed with learning more about the sperm donor, and her friend, Elaine, helps her by taking on a temp job at the sperm bank and breaking into their files, discovering the identity of Grace's donor, a photographer named Peter Kessler (Stanley Tucci). He is single, having an affair with a married woman, and his landscape photographs never include human figures because, he says, "people mess up the composition."

Grace visits Peter's upstate New York studio. They meet, become friends, and then begin dating. Grace tells him she is pregnant and that he is the child's donor father. He is outraged and throws her out. Months pass, and Peter arrives in New York to apologize to Grace, who is now heavily pregnant. He gives her a photograph he had taken, of her. The film ends ambiguously, but suggests that they will become a couple and parent the child together.

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