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Idealistic, nervous, and rigid, Andrew Manson (Robert Donat) takes his first medical job as an assistant to a doctor in a Welsh mining community. The greedy wife of his invalid employer obliges Manson to hand over most of his earnings. But he finds a local kindred spirit in the outspoken Dr. Denny (Ralph Richardson). In a drunken prank, they blow up the town sewer forcing the unwilling government to repair a notorious source of typhoid.

Manson marries a beautiful school teacher (Rosalind Russell) who leaves her beloved classroom to follow him to an even larger mining town. There he is employed by a group practice run on a capitation basis by the miners. In their evenings, the Mansons investigate the problem of chronic cough in miners, linking it to tuberculosis and coal dust--a discovery that they publish. But suspicious miners destroy their laboratory and force them to London and poverty.

A chance encounter with a wealthy hysteric and an old mate (Rex Harrison) raises Manson’s social standing. He opens a Harley Street practice and makes a fortune. His wife regrets the loss of his ideals and the death of his research. She begs him to remember how happy they were in poverty when each day was a noble challenge to take "the citadel" of life. Denny returns to entice Manson into a new group practice funded by community insurance, but Manson flatly refuses. Denny’s accidental death and a blunder by an elite, unethical Harley Street surgeon bring Andrew back to his idealistic senses.

The film closes with his eloquent self defense against charges of irregular practice for having intervened (successfully) in the case of a little girl with tuberculosis. Manson assists as the child is treated gratis with the controversial new pneumothorax operation administered by an American who does not hold a medical degree. Whether or not Manson keeps his license, the audience is confident that his sense of purpose has been restored and that his wife loves him more than ever. He will return both to the comfortably compatible pursuits of research and serving the sick poor.

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As a medical student, Martin Arrowsmith (Ronald Colman) approaches the revered Professor Gottlieb (A. E. Anson) wishing to accelerate his studies into bacteriology research. Gottlieb insists that he complete his clinical training first. But Arrowsmith meets the cheeky nurse Leora (Helen Hayes) and throws over his plans for science in order to earn a marriage-sustaining living as a general practitioner in her native South Dakota.

Assuaging his undying passion for research (in the family kitchen), he takes on the problem of an epidemic of black leg disease of cattle and earns the animus of a veterinarian and the admiration of the Swedish farmers by single-handedly disproving the efficacy of a government serum, developing his own serum, and conducting a controlled trial to prove its worth. His frustrated and unemployed wife--now displaced from her own kitchen--continues to support him, answering always "Yes, Martin. No, Martin. Whatever you say, Martin."

The couple move to New York City where Arrowsmith intends to devote himself full time to science at the side of his old hero Gottlieb in the McGurk Institute (a thinly disguised Rockefeller Institute). In his new laboratory, Arrowsmith utters a prayer for clear vision and humility--a prayer that seems to go unanswered.

Late one snowy night after two years of fruitless work, he discovers that "something" (in the novel, it is bacteriophage) has killed the bacteria he has been incubating. "Is it important, Martin?" asks Leora. He is brutal in his zealous response, his eyes gleaming with the promise of promotion, fame, and fortune. But after days of exhausting labour, he learns that he has been scooped by Felix D’Herelle a (real) researcher at the Pasteur Institute.

Arrowsmith quickly finds a new passion and travels to the Caribbean to conduct research into the effect of a serum on bubonic plague. Gottlieb makes him promise to act like a scientist (not a G.P. or a quack) and to withhold the remedy from half his patients. He tries to convince the colonial authorities of the importance of controlled testing, but is rebuffed with accusations of turning humans into guinea pigs. A black medical graduate of Howard University invites him to a different island where the epidemic is so thick that the people willingly cooperate with the controlled trial.

Leora, who had refused to remain in New York, is now left behind. The film implies clumsily that the now solitary Arrowsmith--ecstatic to be back in the research trenches--has a romantic encounter with Joyce, a beautiful stranded tourist (Myrna Loy). Meanwhile, Leora contracts plague from a cigarette, which has absorbed plague germs from Martin’s sloppy lab technique, and which she smokes because of Martin’s inattention and abandonment. She dies miserably and alone.

Crazed with remorse, Arrowsmith abandons his scientific principles and allows the entire population to be treated with the serum after all. The epidemic is arrested. But Martin knows that his success does not justify his scientific sin. Still grieving for Leora, he returns to New York to much fanfare, but is unable to find absolution from Gottlieb who has just had a stroke. He runs out on his lover, his institute, and a press conference to join a friend who is establishing a Walden-like institute dedicated to pure research in Vermont.

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During the Nazi occupation of Paris, the deranged doctor Petiot (Michel Serrault) abuses the trust implied by his profession to "help" frightened Jewish citizens. By day, he conducts his clinic and supports his family with a kindly obsession. By night, he leads his victims from a metro-station rendezvous to his apartment, their worldly possessions dragged in a trailer behind his bicycle. He then administers a "vaccine" and locks the now poisoned refugee in a room to face an agonizing death alone.

The doctor takes the possessions of his victims, and dismembers and incinerates their corpses in a makeshift crematorium in his basement. In March 1944, the nauseating black smoke betrays his activities; however, the now notorious doctor vanishes, abandoning his wife and son. Following the war, he is living incognito as a soldier pursuing war criminals and collaborators. But he is identified by his fascination with the Petiot case and his handwriting. In the final scene, dozens of people stand at a long table silently sorting through clothing, jewelry, books, seeking belongings of their loved ones who became the doctor's victims.

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A dark-eyed, ten-year-old Indian pauses for a moment in playing with her friend to explain that she is soon to be married, but would rather stay at home and in school. Her friend announces that she will never get married; she wants to become a policeman. Another smiling child in Yemen wants to be a doctor to help people. She looks forward to wearing the hijab. Little girls with great family burdens, and others who have no families, all expect to become mothers themselves. They talk about their daily routines.

A confident child in Peru cooks, cleans, does laundry, and then washes, dresses and feeds her younger siblings, before putting on her crisp uniform and going off to school. Two shy girls from Africa describe the painful ritual of circumcision--and a "cutting" ceremony is observed from a modest distance. One talks about her separation from her mother and life as a slave.

Interspersed are scenes of the children playing. Commentary emphasizes how soon these little girls must become women and how much of the world's work and how little of its wealth belong to them.

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A three-year old girl with globular cheeks patiently allows her calligrapher father to brush letters on her face and lips, as he recounts the story of creation: "And when God saw it was good, he signed it." Gently, he turns her round to sign at the base of her neck. Several years pass with the ritual repeated, accompanied by a cheery song that had been popular when her parents were first in love.

An aunt gives her a diary (or "pillow book"), and so begins N's obsession with writing. The tender scenes are marred by the brusque visits of her father's publisher (Yoshi Oida), with whom he has a sexual relationship. Through the child's eyes, the father is forced to prostitute his body for his written work.

Grown into a beautiful woman, Nagiko (Vivian Wu) escapes an unhappy marriage with the misogynist office boy from the publishing house by fleeing to Hong Kong. She works as a model and seeks solace (and her absent parent) in a perpetual quest for calligraphers who will become her lovers and write on her body.

She tries unsuccessfully to print her own work with the publisher as a kind of revenge for the power he held over her father. Her lover, the polyglot translator, Jerome (Ewan McGregor), urges her to write on his body for "submission" to the reluctant publisher. Jerome is already yet another of the publisher's lovers. Nagiko agrees and the plan works, but she is overcome with jealousy and spurns Jerome.

Counseled by a disingenuous friend, the unhappy Jerome takes a supposedly temporary poison in order to win her back; her affection is restored, but the poison kills him. The publisher exhumes Jerome's body, for a gruesome harvest of his skin and her words. Disconsolate and enraged, Nagiko submits book after book of her work to the publisher, each chapter written on a different male body, some perfect, some dilapidated, all her lovers.

Finally she sends "Book 13, the Executioner" on the sumo-wrestler-like body of a man who slashes the publisher's throat. Nagiko returns to Japan where she gives birth to Jerome's child and the cheerful song of her childhood returns as she writes on the infant's face.

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In the year 2000, Nafas (Niloufar Pazira) a 29-year old Afghan-born Canadian journalist travels back to her homeland in search of her sister. The sister was maimed by the long war, and her life under oppressive Taliban rule is no longer worth living; she has resolved to commit suicide on the last solar eclipse of the century.

Dependent for her travels on the uncertain help of men, Nafas encounters many other charismatic women hiding under the seclusion of the burqas. The inquiries she makes to find her sister raise the veil just enough to reveal the torment of Afghan women, deprived of rights, education, and basic health care. A doctor must question his women patients, who are hidden from him by a canvas wall, through a child intermediary; he does not touch them. The ending is inconclusive.

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In the poem, persimmons are a symbol of several elements that have figured importantly in this Chinese narrator's life: they stand for painful memories of cultural barriers imposed by language and custom, and for a present-day loving connection to an elderly, blind father. The poet begins with a schoolboy incident in which he was punished for not knowing the difference between "persimmon" and "precision" and makes a play on other words which sound similar and "that got [him] into trouble." He takes revenge later, when the teacher brings to class a persimmon that only the narrator knows is unripe, as he "watched the . . . faces" without participating. Persimmons remind him of an adult sensual relationship with Donna, a Caucasian woman, and of his attempts to teach her Chinese words which he himself can no longer remember.

The second part of the poem describes the role persimmons have played in his father's life and in their relationship. To comfort his father, gone blind, the narrator gives him a sweet, ripe persimmon, so full and redolent with flavor that it will surely stimulate the senses remaining. Later yet again, the father and he "feel" a silk painting of persimmons, "painted blind / Some things never leave a person."

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This strong, powerful poem of grief for the death of an infant son in an intensive care unit is written by a poet who lost two of his five children. The rhythm of the poem is jazz, pulsing and pulsating, with well-controlled rests. Some words are run together: " . . . mamaborn, sweetsonchild / gonedowntown into researchtestingwarehousebatteryacid" which evokes (among other things) the frenzied atmosphere of a neonatal intensive care unit and the seemingly inevitable rush towards death.

Much of the poem deals with the distrust of the medical community, which is emphasized by the divide of race: the white doctors and nurses in white uniforms versus the African-American patient and family. The frustration of dependence on others is painful for the father during the nightmare of his baby’s dying. However, the poet reaches a higher level of understanding about his pain and grief; he acknowledges that the baby did receive all that medicine had to offer and he recognizes the complicated responsibilities one acquires by experiencing a loss.

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This extraordinary book is ostensibly "about" a doctor caring for persons with HIV/AIDS. That it is, but it is also a book containing multiple texts. It is a doctor's personal journey toward understanding the multiple meanings of HIV/AIDS for those who have it and those who care for them. It is the story of a physician, an Indian, born in Ethiopia to Christian expatriate teachers, in America since 1980, now in Johnson City, Tennessee, still trying to determine the meaning of "home."

It is, at the same time, a glorious pastoral account of practicing medicine in Tennessee--here making a house call to Vicki and Clyde, whose trailer is perched on the side of a mountain, now traveling through the Cumberland Gap to a cinder-block house to see Gordon, another native son who has come home to die. On still another level it is the story of a man trying to understand what it is like to be gay; a man trying to integrate his passion for his work with his life at home; a man trying to explain to his wife (and sadly, even some of his peers) his commitment to caring for persons infected with the virus.

The portraits Verghese draws of his patients are extraordinary: local boys now men, now sick, returning to Johnson City to be cared for by family; a woman infected by her husband who also infected her sister; a highly-respected couple from a nearby city seeking privacy, even from their grown children. Finally, part of what makes Verghese such a fine writer is that he is able to do so without romanticizing his relationships with his patients, and without self-congratulatory accolades for the kind of care he provides.

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Sister Outsider is a collection of essays focusing on race/racism, gender/sexism, sexual identity, and social class as these are enacted in a white-supremist, heterosexist, capitalist patriarchy (i.e. the United States). As a Black woman, lesbian, feminist, mother, poet, essayist, and political activist, Lorde's essays in this collection include her often quoted "The Master's Tools Will Never Dismantle the Master's House," an essay that radically challenges how white people "learn about" racism, or how men "learn about" women: "Women of today are still being called upon to stretch across the gap of male ignorance and to educate men as to our existence and our needs. This is an old and primary tool of all oppressors to keep the oppressed occupied with the master's concerns . . . ."

Her essay "Poetry is Not a Luxury" suggests that poetry is "illumination," and is a way to wed ideas and feeling, a way "we help give name to the nameless so it can be thought. The farthest horizons of our hopes and fears are cobbled by our poems, carved from the rock experiences of our daily lives." Other titles include "Sexism: An American Disease in Blackface," "Man Child: A Black Lesbian Feminist's Response" (on being the lesbian mother of a son), and "The Uses of Anger: Women Respond to Racism."

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