Summary:

Dr. Sacks was growing up in London during World War II and had a very traumatic experience when he was sent away from his home for protection from the bombing. He and his brother were sent to a boarding school, where they were beaten and underfed. Sack's home had been filled with a wonderful extended family of physicists, mathematicians, teachers, and chemists, in addition to his parents who were both practicing physicians. Being unusually bright and talented, Sacks responded to a wide variety of stimuli when he returned to this environment.

He became fascinated with the chemistry of metals and with the periodic table of elements. An uncle, for whom the book is named, was a manufacturer of light bulbs with tungsten filaments and encouraged him in setting up his own chemistry laboratory in the family laundry room, to do experiments. The family allowed him a great deal of freedom, which encouraged his creativity.

In writing about these experiences Sacks includes the history of the development of chemistry concepts that fascinated him. It was only much later that his interests moved on to the natural sciences and medicine. He says that his parents had been tolerant and even pleased with his early interests in chemistry but by the time he was fourteen they felt that the time for play was over. He kept a journal from the age of fourteen and took advantage of every opportunity to read broadly and experience nature, music and art.

In retrospect, however, Sacks felt that life was shallower after he left behind his passion for chemistry. He says that he dreams of chemistry at night. This description of such intense interest in the world around him and the people he read about or knew explains a great deal about his great success as a neurologist and as a remarkable story teller.

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This essay provides a rich and detailed critique of the medical view of women in 19th-century America. As the keywords suggest, the authors cover many topics. To mention a few: the coming of male dominance in medicine; the patronizing and disabling characterization of women as "weak, dependent, diseased," and naturally patients; S. (Silas) Weir Mitchell and his treatment of Charlotte Perkins Gilman; the social role of female invalidism in upper middle class culture; the "scientific" view of woman as evolutionarily devolved; and what the authors call "the expert-woman relationship."

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Some interesting and very odd characters (including a few scientists and researchers) inhabit the eleven short stories in this collection. In "Concerning Mold Upon the Skin, Etc.," Anton van Leeuwenhoek creates his first microscope and becomes so absorbed by the invisible worlds revealed to him that he neglects his own family. "Nowhere" is the tale of an old anatomy professor who aspires to spice up the curriculum by obtaining a corpse for his students to study. "Tumbling" recounts the difficult life of a young woman understandably haunted by the possibility that she may inherit Huntington’s chorea from her father and her inspired liberation of over one thousand laboratory mice.

In "Chloroform Jags," a professional midwife self-experiments with chloroform "not to escape time but to dissolve time." Other stories describe the execution of an elephant; the murder of a physician who happens to be an important figure in the French Revolution; a woman with a talent for insomnia who has not slept for six months; a psychoanalyst and his patient; an eighteenth century blind beekeeper; and Dorothea Dix, an early advocate for the humane treatment of the mentally ill.

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The author, a Canadian physician-historian-educator, blows the dust off the shelves of medical history with this fascinating text designed for medical students, educators, and those with an interest in history of medicine. Duffin begins this survey of the history of Western medicine with a glimpse at a pedagogical tool designed to spark the interest of even the most tunnel visioned medical students: a game of heroes and villains. In the game, students choose a figure from a cast of characters selected from a gallery of names in the history of medicine.

Using primary and secondary sources, the students decide whether the figures were villains or heroes. The winner of the game is the student who first recognizes that whether a person is a villain or hero depends on how you look at it. This philosophy imbues the entire book, as this treatise is not a tired litany of dates, names and discoveries, but rather a cultural history of the various times in which medical events occurred.

The book is organized by topics which roughly follow a medical school curriculum: anatomy, physiology, pathology, pharmacology, health care delivery systems, epidemiology, hematology, physical diagnosis and technology, surgery, obstetrics and gynecology, psychiatry, pediatrics, and family medicine. The last chapter, entitled "Sleuthing and Science: How to Research a Question in Medical History," gives guidance to formulating a research question and searching for source material. Fifty-five black and white illustrations are sprinkled throughout the book, as well as 16 tables.

Direct quotes from historical figures, such as Galen and Laennec, as well as excerpts from writings of eyewitnesses of events, anecdotes and suggestions for discussion, appear in boxes within the chapters. Many of the chapters contain discussion about the formation of professional societies. Each chapter ends with several pages of suggested readings and the third appendix delineates educational objectives for the book and individual chapters. The other two appendices list the recipients of the Nobel Prize in Physiology or Medicine, and tools for further study, including titles of library catalogues, and resources in print and on-line.

Although the book is a survey covering multiple eras and topics, each chapter contains choice tidbits of detail. For instance, the chapter on obstetrics and gynecology includes the story and photograph of Dr. James Miranda Barry, the mid-nineteenth century physician, surgeon and British military officer, who was discovered to be a woman at the time of her death. The impact of the stethoscope on the practice of medicine is explored in depth in the chapter, "Technology and Disease: The Stethoscope and Physical Diagnosis."

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This sketch is teeming with images: in what appears to be a science lab, two researchers stand in the background, surrounded by gray lab equipment; one peers into a microscope. In the bottom of the frame a horse and cow flank three sheep. At the center stands a muscular baby, loosely draped in a white cloth and held up by a nurse in a white apron and cap. To his left stands a rather grim looking doctor, who holds the baby's arm with one hand and injects a vaccine with the other.

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The story opens on the day that Ridgeon, a prominent research doctor, is knighted. His friends gather to congratulate him. The friends include Sir Patrick, a distinguished old physician; Walpole, an aggressive surgeon; Sir Ralph Bloomfield Bonington, a charismatic society doctor; and Blenkinsop, a threadbare but honest government doctor. Each one has his favorite theory of illness and method of cure. These are incompatible--one man's cure is another man's poison. Nonetheless, they all get along.

A young woman (Mrs. Dubechat) desperately seeks help for her husband from Ridgeon, who has evidently found a way to cure consumption by "stimulating the phagocytes." Ridgeon initially refuses, but changes his mind for two reasons--Dubechat is a fine artist and Ridgeon is smitten with his wife.

When the doctors meet Dubechat, however, they find that he is a dishonest scoundrel. Ridgeon eventually decides to treat Blenkinsop (who also has consumption) and refer the artist to Bloomfield Bonington, this insuring that he will die. In the end Ridgeon justifies his behavior as a plan to let Dubechat die before his wife find out what an amoral cad he actually was. This, in fact, happens and Dubechat's artistic reputation soars.

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Loosely based on true events in the eighteenth century, this novel chronicles the intersection of two lives. Charles O'Brien, an exceptionally large man, travels along with friends from Ireland to England to exhibit himself. He is a giant in more ways than one. In addition to his immense size, he is also intelligent, compassionate, articulate, and a gifted storyteller.

John Hunter, a Scottish anatomist and scientist, is obsessed with experimentation, discovery, and collection. He instructs graverobbers, dissects corpses, and self-experiments with syphilis. Although both men are remarkable and abnormal, it is the scientist rather than the giant who emerges as the genuine freak.

After the colossus dies, Hunter purchases O'Briens's body for study and his collection. At the end of the story, the giant's bones still hang in permanent display but Hunter's portrait is noted to be fading toward extinction.

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The multiple plots of Our Mutual Friend, Dickens's last complete novel, twine around the miser John Harmon's legacy of profitable heaps of refuse ("dust"). Harmon dies and leaves the dustheap operation to his estranged son John, on the condition that he marry Bella Wilfer, a young woman unknown to him. When a body found in the Thames is believed to be the younger Harmon, travelling home to receive his inheritance, the dustheaps descend instead to Harmon's servant Noddy Boffin ("The Golden Dustman").

Boffin and his wife respond to their new status by hiring Silas Wegg, a "literary man with a wooden leg" to teach Boffin to read; arranging to adopt an orphaned toddler from his poor great-grandmother; and bringing the socially ambitious Bella Wilfer into their home, where she is watched and evaluated by John Rokesmith, a mysterious young man employed as Boffin's secretary.

Rokesmith is actually John Harmon, who has survived betrayal and attempted murder and is living incognito so that he can observe Bella. Boffin's negative transformation by his wealth, Bella's moral awakening as she witnesses the changes wealth produces in Boffin and in herself, and the developing love relationship between Rokesmith and Bella form one key sub-plot.

Another is the romance between gentlemanly idler Eugene Wrayburn and Lizzie Hexam, the daughter of the waterman who finds the drowned body. Class differences and the obsessive love and jealousy of schoolmaster Bradley Headstone threaten their relationship, but they are finally married with the help of the crippled dolls' dressmaker Jenny Wren. The smaller plots that interweave these sensation/romance narratives comment on the hypocrisy of fashionable life ("Podsnappery") and the destruction of the family lives of both rich and poor by an industrialized, materialistic society.

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The action takes place in 1968 at the offices and laboratories of a large pharmaceutical company. Dr. Michael Daly is replicating a series of psychological experiments purportedly designed to enhance the efficiency of learning. In these experiments the actual subjects are asked to inflict electric shocks on mock "subjects" who fail to give correct answers to mathematical problems.

The mock "subject" is ostensibly wired to an electric chair. In fact, she is really an actress pretending to be in pain. Even though she cries out in agony every time she makes a mistake, the actual subject--an ordinary person, who is just following instructions--pulls a switch that (he believes) gives her a progressively higher jolt of electricity.

The subjects almost invariably follow the evil instructions. In fact, one of them, Mr. Harley-Hoare, a sniveling and obsequious office worker, is truly outraged at Sally (the mock subject) for not learning faster. Against the backdrop of the Vietnam War and the corporate world, this play re-explores the issue of personal responsibility for evil actions.

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Margaret is a sculptor whose detached and unaffectionate physician-husband has just exited their marriage. Depressed, she is in dire need of work to survive and to cover the costs of urgently needed dental work. She gladly accepts a museum commission to recreate a life-sized likeness of Lucy, the Australopithecus afarensis hominid.

The plan is to reconstruct the body using casts of the fossil bones and to depict a single moment in Lucy's past, as captured by the fossilized Laetoli footprints. Made by a hominid pair, the prehistoric footprints show how the smaller creature--Lucy--hesitated in her unknown journey 3.6 million years ago.

As Margaret reassembles her ancestor and situates her plausibly in that mysterious moment, she rediscovers her own animal body, its senses, needs, and beauty--and she begins to reassemble her life.

In the end, she appears to find love and joy with a musician whom she first encounters on a purely physical basis. Yet she is comfortable with an ambiguous future.

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