Summary:

Manuela (Cecilia Roth) a nurse who works in a transplantation unit, witnesses the accidental death of her romantic son, Esteban, as he chases a car bearing the famous actress, Huma Roja (Marisa Paredes), from whom he wants an autograph. Esteban had longed to know about his absentee father, but his mother had always refused to tell him. His heart is transplanted, and Manuela is shattered by grief, leaves her work, and sets out to recover her past.

Obsessed with her son’s obsessions, Manuela trails the famous actress, Huma, who gives her a job. She finds old friends in the underworld, and a beautiful nun, Rosa (Penélope Cruz), who works with the poor and plans to go abroad. Soon it emerges that Esteban’s father is "Nina," a transvestite prostitute, and that Rosa is not only pregnant by him/her, she has also contracted AIDS.

Rosa’s austere mother was unhappy about her decision to become a religious, but she is even more horrified by her daughter’s pregnancy and illness. Initially reluctant, Manuela nurses Rosa and after her death, she adopts the infant son who is of course named Esteban.

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