Few books have received the attention, both positive and negative, that The House of God has garnered since its publication over 30 years ago, and it continues to evoke strong feelings in readers today.  Editors Kohn and Donley argue that, "like all art, it gives rise to a range of emotions and makes us wonder more deeply about this world we live in, specifically the world of medical training" (xii). This range is apparent in the essays.  Family physician Howard Brody's essay focusing on the Fat Man's laws in the House of God argues that they actually contain a great deal of medical wisdom and "sneak in" elements of primary care; physician and historian Kenneth Ludmerer contends that not only was the portrayal of residency education accurate for that time but that many of the problems remain; psychiatrists Neeta Jain and Dagan Coppock examine Shem's claim about the cathartic process of writing The House of God,  likening it to their similar experience of crafting an anthology, which "made the burden of human suffering and the exhaustion of medical training more bearable" (121).

Other essayists are less enthusiastic about the merits of the book.  Nurse and scholar
Amy Haddad writes that her experiences were dramatically different from those described in the book and were marked by discrimination and verbal abuse from attending physicians. Physician and poet Jack Coulehan argues that students reading The House of God "internalize the message that clinical training is dehumanizing without sufficiently noticing that the group most dehumanized in the novel is patients. . . . It glorifies gallows humor but avoids self-deprecating humor" (115). Other noteworthy essays include Julie Aultman's assessment of virtue in The House of God, and Susan Mates's short story "The Madwoman in the Attic," which finds the much-maligned character Jo the author of her own "laws."

The final two essays by Surrey and Bergman offer insights on the book and their personal, spiritual, and professional journeys taken since its publication. The collection is a valuable scholarly contribution to understanding the educational, historical, and literary significance of this iconic novel.