Dr. Robert Weiss passes through the town of Sankt Vero in the Tirol and rents a room from the Lukasser family. During the night, the Lukasser's son, Niki, develops acute appendicitis; the visiting doctor operates right there on the kitchen table, saving the boy's life. Years later, when war rages in Europe, the Jewish doctor returns to Sankt Vero and knocks on the Lukasser's door. He tells of soldiers forcing men, women, and children into railroad cars, and how he himself--he who had saved Niki years before--needs asylum.

To hide Dr. Weiss, Mr. Lukasser boards him up in a small room in the back of the hayloft, a space one meter wide and three meters high. For two years, the doctor exists in this box. Niki and his friend, a blind girl named Sigi, bring Dr. Weiss food once a day and, for ten minutes or so, they stay and talk. Sustained by Niki and Sigi's lives--the stories of their discoveries of sexuality, cruelty, and love--the doctor survives.

Although Sigi is blind, she has the insight to recognize and try to alleviate the doctor's growing depression by encouraging him to tell his own stories. It is through these stories and through the doctor's observation of Sigi and Niki's blossoming adolescence and struggles with morality that we experience both the doctor's confinement and the powerful conflicts and transformations that rage behind the doors of Sankt Vero.