An American physician's life is irrevocably bisected by World War I. Before volunteering for medical duty in the war, Dr. William Lloyd's existence was structured, safe, and even obedient. After his experience supervising a hospital in France, his life becomes uninhibited, tumultuous, and eventually dangerous.
After the war ends and he returns home, Dr. Lloyd soon divorces his wife and leaves his family. He returns to Europe with the sole purpose of being reunited with Jeanne Prie, a bewitching and extraordinary nurse he worked with in France. She is also a dedicated microbiologist and possesses some of the characteristics of Joan of Arc. Dr. Lloyd has become infatuated with her. Ironically, he dies a victim of scientific research after inoculating himself with an experimental serum that he hoped might be a successful vaccine.