Dominating the image, a vengeful Satan with arms outstretched stands upon Job's prone body dispensing boils from a vial with his left hand while shooting arrows at him with his right. Job's head is thrown back and his hands are lifted off the ground in a sign of agony. His weeping wife kneels at his feet. The background is minimal yet dramatic with its dark swirling clouds, bright setting sun, and Satan's huge blood red wings.
Blake's vigorous imagination is seen in this painting where he shows Adam and Eve discovering Abel's body as Cain prepares to bury it. Adam and Eve are kneeling in horror next to Abel's white and rigid body. Adam looks with shock at Cain, who runs away, tearing at his hair. Eve throws herself over Abel's body in a gesture of extreme grief. Her arms form a circle as she bends over Abel with her head thrown down and her hair falling in waves over his body. Although posed and awkward, Adam and Eve's gestures effectively express their emotions. The newly-dug, dark long horizontal grave, emphasized by the shovel laying parallel to it in the foreground, creates a deep gash that separates the fleeing son from his parents.