Summary:

This film tells the story of Alfred Kinsey (Liam Neeson), the scientist who famously changed his focus in mid-career from the study of gall wasps to the study of human sexuality and through his publications on male and female sexuality (1948, 1953) revolutionized the way we think and talk about sex. Kinsey entered adult life with the classic Boy Scout's view of sex that it was best not to think about it. (He collected a million gall wasps instead.) But under the influence of one of his students, Clara McMillen (Laura Linney), who later became his wife, and listening to the questions some students were asking about sex, he decided to teach a course at Indiana University on human sexuality. "Sexual morality needs to be reformed," he proclaims, and "science will show the way."

He begins doing statistical research on individual sexual behavior, training his interviewers to be open and neutral as they encounter a very wide variety of behaviors. He also encourages them to experiment sexually among themselves, and later even to participate in sexual encounters filmed for research purposes. Naturally, not everyone accepts this readily, and there are problems between Alfred and Clara, among the research assistants, and eventually between the whole project and Indiana University and the Rockefeller Foundation.

Rockefeller withdraws its support, complaining that Kinsey is preaching in public, and Clara tearfully complains that some social restraints are needed to keep people from hurting each other. The assistants struggle with the ties between sex, which is part of the experiment, and love, which is not. Kinsey continues striving, but with much reduced means. The film ends with video clips of interview subjects speaking strongly about the benefits that Kinsey's revolution has brought to them, one woman concluding: "You saved my life, sir!"

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Born in 1728 the tenth child in a struggling Scottish farm family, John Hunter was a wayward and unteachable child who spent most of his time outdoors. At the age of 20, with no prospects and having lost his father and 6 siblings, he wrote for help to his older brother William, who was practicing midwifery in London and had just opened England's first anatomy school, one featuring the revolutionary opportunity for students to dissect their own cadavers.

John rode the 400 miles to London on horseback, apprenticed with great success under William, learned dissection, then surgery, and went on to become a supremely gifted anatomist and surgeon, one whose brilliant and tireless experimentation broke with ancient and outmoded medical traditions and established the foundation for modern science-based surgery. (When John arrived in London, the city's Company of Barber-Surgeons had only just dissolved to allow surgeons to organize themselves independently of barbers.)

One of his most important activities in working for his brother--and which continued when he made his own way--was the procuring of cadavers, which because of the customs of the time involved him intimately in the grisly business of grave-robbing.

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Thirty-one-year-old waitress and aspiring (but inexperienced) boxer Maggie Fitzgerald (Hilary Swank) tries to get aging trainer-coach Frankie Dunn (Clint Eastwood) to take her on, but where Maggie is unstoppably optimistic, Frankie is worn out, even burned out, and he repeatedly refuses. The two are brought together by Frankie's assistant, ex-fighter Eddie "Scrap-Iron" Dupris (Morgan Freeman). Freeman, whom the other characters call Scrap, narrates the film.

Maggie and Frankie have their ups and down, but Maggie rapidly becomes a formidable boxer, a great favorite with fans. Eventually she finds herself in the ring as challenger for the world welterweight title. The unscrupulous defender delivers an illegal punch to Maggie, resulting in a fall that leaves her paralyzed below the neck.

At this point the story turns from boxing to Maggie's injury, which is incurable and worsening because she is bedridden. After Maggie loses a leg to bed sores, she tells Frankie that she doesn't want to go on, and she asks him to put her out of her misery. Short as her career has been, she has known success and happiness beyond the dreams of her dirt-poor upbringing, and she wants to leave life while she can still remember those good things.

Frankie, a serious Catholic, has religious qualms. His priest tells him not to get involved. From his own point of view, Frankie has come to feel attached to Maggie, and at first he steadfastly refuses Maggie's request. Maggie, unable to act in any other way, bites her tongue violently in an attempt to bleed herself to death. After witnessing her agony, Frankie tells the priest that keeping Maggie close to him--in other words, not killing her--has come to feel like a sin. He then acts to rid himself of that sin. He covertly removes her air supply and then injects her with adrenalin. Frankie does not return to his gym, vanishing without a word.

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While riding his bicycle, Paul Rayment, a 60-year-old Australian photographer, is struck by a car. He winds up in the hospital, has a leg amputated, and returns to his quarters to contemplate his future and deal with a series of nurses sent by the hospital social worker. Paul is divorced and has no living family.

His future looks bleak, and none of the nurses is satisfactory until the appearance of Marijana, a middle-aged Croatian woman with a young daughter, a teenage son, and a husband. The narrator gradually falls in love with Marijana, but by degrees his lust sublimates into an intense devotion to helping her son Drago survive his motorcycle phase and achieve his educational and professional objectives.

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This is a collection of two dozen case studies, written for non-medical readers, of patients with right-brain disorders. The chapters are divided into four groups: "Losses," dealing with loss of memory, cognition, and proprioceptive sense; "Excesses," with tics and other cases of overabundance; "Transports," with seizures and various "dreamy states," and "The World of the Simple," concerning mental retardation. In every case, Sacks focuses on the interior or existential world of the patient as the foundation of diagnosis and treatment. Sacks argues that this approach is appropriate for the right hemisphere, which compared to the left is less dedicated to specific skills and more dedicated to a "neurology of identity."

Sacks openly proposes these studies as a corrective to the field of neurology, which has tended to focus on the left hemisphere and therefore, he argues, has wound up treating patients solely in terms of specific deficits, often to their detriment. In "the higher reaches of neurology," and in psychology, Sacks argues, disease and identity must be studied together, and thus he recommends that neurologists "restore the human subject at the centre" of the case study. Sacks warmly recommends music, story-telling, and prayer as therapies that work by ignoring physiological defects and speaking to the patient's spirit or soul.

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This book contains six medical case studies in which hope, or lack of it, played a role in the outcome. Five stories are of Groopman's cancer patients, the sixth the story of his own recovery from severe chronic lower back pain. The book concludes with an account of Groopman's search for scientific answers to the questions that inspired the book: How is the cognitive-emotional complex of hope formed in the mind? How might that complex affect the chemistry of the brain? And how might that, in turn, affect the physiology of the body in a way that would be relevant to healing?

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In his mid-twenties and having been estranged from his family since his mid-teens, Andrew Largeman (Zach Braff) returns home to New Jersey for a few days to attend his mother's funeral. The world he meets there (in "The Garden State," ironically) is persistently unnatural and weird. His old school friends are leading grotesque and diminished lives, and Andrew dislikes and dreads his father, a psychiatrist played by Ian Holm, because of the prehistory we discover in mid-film. (Andrew's mother had suffered with depression, and young Andrew hated her for it. One day, aged 9, he gave her a shove, and freak circumstances led to a hard fall and her becoming paraplegic. Fifteen years later she has died in her bathtub, perhaps a suicide--although that isn't mentioned in the film.)

Andrew keeps his psychic distance from all this, with one fortunate exception: By chance he meets Samantha or "Sam" (Natalie Portman), a sweet loopy girl his age who lives in a child-like room in her mother's house and has a tendency to lie a lot and then confess. She and Andrew take a liking to each other, and a relationship develops that eventually helps Andrew come to terms with his mother's death, with his role in the tragic prehistory, and, thus, with his father and his own life, now able to begin, finally, as a young adult.

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Kirk, a man in his 50s with highly metastasized kidney cancer, presents himself to Dr. Groopman after having been turned away as a helpless case by several respected cancer clinics. He tells Groopman that he is a risk-taking venture capitalist and is willing to take any medical risk on the chance that it will save him. After pondering the ethics of the situation and the nature of informed consent under such conditions, Groopman agrees to treat Kirk. He proceeds to devise a highly risky (and untried) combination of chemotherapeutic agents. The course of treatment is excruciatingly difficult, but the experiment succeeds, and Kirk's cancer goes into complete remission.

Kirk calls it magic, a miracle, and the hospital interns call it a "fascinoma," a case defying normal expectations. Groopman releases Kirk to home and weekly checkups with a local internist, but in doing so he notices that Kirk's mood has mysteriously changed. He has lost the "piss and vinegar" of their earlier contact. Kirk continues to improve physically, traveling and playing golf and even tennis, but Kirk's wife soon reports that Kirk has stopped reading the newspapers he used to devour, which now collect in their driveway.

Several months later some physical symptoms return, and Kirk's cancer is back. A month later he is dead. In talks with Kirk near the end, Groopman discovers that Kirk's brush with death had brought with it a new and sharply negative view of himself as selfish and disconnected from the world and other people. Suddenly all his financial success seemed to him "pointless," and, since his life contained nothing else, it seemed to him a waste, and he felt it was too late to live it over. What Kirk ironically calls "my great epiphany" seems to have undone his doctor's "magic."

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Selzer tells four stories of surgical loss: a surprise loss on the operating table, the drowning of a sick child in a flood in wartime Korea, the sudden death of a professor due to a perforated ulcer, and the loss of some facial mobility in a young woman following the removal of a tumor in her cheek. As we move from one vignette to the next, the narrator's mood goes from despair to accepting to redeemed, with various forms of love the agent.

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Selzer begins by describing an anonymous painting of Vesalius at the dissecting table, about to cut into the cadaver in front of him, yet glancing over his shoulder at a crucifix on the wall behind him. He then tells two medical stories in which spirituality has played a crucial role.

In the first, a man who has repeatedly refused to have a brain cancer operated on turns up one day healed, attributing it to the holy water a family member brought back from Lourdes. In the second, the Dalai Lama's personal physician does rounds in an American hospital and, using ancient techniques, diagnoses correctly, and in some detail, a case of congenital heart disease.

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