Showing 41 - 49 of 49 annotations tagged with the keyword "Genetic Engineering"

Life Support

Gerritsen, Tess

Last Updated: Jan-13-2003
Annotated by:
Kohn, Martin

Primary Category: Literature / Fiction

Genre: Novel

Summary:

Set in contemporary Boston, this medical thriller not only gets the reader's blood moving, but also raises some important ethical questions: How do corporate interests influence the judgment and character of physician researchers? To what length should older persons go to slow down the aging process? How does one's lifework of health care fit in with obligations to one's family?

View full annotation

Annotated by:
Coulehan, Jack

Primary Category: Literature / Fiction

Genre: Novel

Summary:

The story takes place in the distant future on a world called New Sparta, shortly after the Irredentist rebellion has been put down. Edward Maret, a wealthy and likeable young man, is about to get married, but doesn't realize until too late that he has enemies close at hand. As a result of their betrayal, Edward disappears into the bowels of the police establishment, only to emerge as a zombie-like cyborg (AX-17). After surviving several years as a cyborg-soldier who has no memory of his human life, AX-17 is captured by the alien Kliya, who initiate a process that leads the cyborg to regain his human identity.

Edward Maret re-emerges--a man betrayed, a man who suffers incalculable pain, a man who has lost everything, including the love of his life. The brutalized man journeys across the galaxy to the Confederation, where physical existence has become a burden to humans, who spend most of their "real" lives in a virtual world of wish fulfillment.

Eventually, he returns to New Sparta with a new identity and a plan to obtain his revenge. Piece by piece the elaborate plan falls into place. Yet at the climax, Edward is forced to look deeply into his character and motivation, while coming to terms with his past.

View full annotation

Self-Portrait with Halo

Gauguin, Paul

Last Updated: Feb-11-2000
Annotated by:
Bertman, Sandra

Primary Category: Visual Arts / Painting/Drawing

Genre: Oil on wood

Summary:

Dividing the background expanse of red from yellow, and surrounded by a halo, three apples--green, red, and purple, four yellow papyrus blossoms, and a snake held between the fingers of the artist's hand, a disembodied head appears caricature-like in this self-portrait.

View full annotation

Dawn

Butler, Octavia

Last Updated: Nov-25-1998
Annotated by:
Stanford, Ann Folwell

Primary Category: Literature / Fiction

Genre: Novel

Summary:

The Earth has been destroyed in a nuclear holocaust and a group of unconscious survivors have been taken by the alien Oankalis to the mother ship and placed in "sleeping" pods for some 250 years. One of the humans, Lilith Iyapo, is awakened and slowly trained by the Oankali not to be afraid of their horrifying (to humans) appearance. She comes to an uneasy truce and trust in the Oankali's explanation of where she is and her role: she has been chosen to awaken a select group (based on her reading of detailed personal resumes).

As she awakens them, one by one, she confronts their anger and confusion and, eventually, their resistance to the notion of gene trading proposed by the Oankali. Lilith becomes a mediator between the humans and the Oankalis, giving birth to a son interbred by her and an Oankali.

View full annotation

Inter Ice Age 4

Abe, Kobo

Last Updated: Mar-05-1998
Annotated by:
Fefferman, Stanley

Primary Category: Literature / Fiction

Genre: Novel

Summary:

The prelude describes a tidal wave approaching Japan. The story is a first-person narrative by Professor Katsumi, inventor of a self-programming computer which can predict the future. Katsumi and his assistant, Tanamogi, plan to predict the future of a private, individual destiny. They choose a subject from the street and follow him. The next day's paper announces his murder.

To solve the case and forestall suspicion, Katsumi downloads the contents of the man's brain, reconstructs his existence, and questions him/it. The victim did not see his murderer, but he tells the team his mistress had sold her aborted foetus for 7000 yen. Then the mistress is murdered. Katsumi's wife has a forced abortion and receives 7000 yen. Katsumi suspects an organization. His assistant Tanamogi volunteers the name of an organization experimenting with extra-utero development of foetuses, and arranges for Katsumi to visit their lab. Gradually Katsumi learns of a vast conspiracy to create an underwater nation, complete with genetically altered water-oxygenating humans and animals, bred in anticipation of the predicted destruction of Japan by a tidal wave.

View full annotation

The Cobra Event

Preston, Richard

Last Updated: Feb-19-1998
Annotated by:
McEntyre, Marilyn

Primary Category: Literature / Fiction

Genre: Novel

Summary:

The threat of biotechnological warfare and/or terrorism is the focus of this carefully researched and riveting novel by the author of The Hot Zone. The term "science fiction" doesn't quite do justice to this tale which lies just to the other side of Preston's usual domain of literary nonfiction. Though the particulars of this story of a genetic engineer who designs lethal virus bombs to thin the population and the counterterrorist group of scientists who attempt to stop him are fictional, the possibilities of such threats are real.

The counterterrorists are a motley and sometimes contentious group of recruits from the FBI, the Centers for Disease Control (CDC), and the U.S. military. Their agendas and methods differ, but the immediate death threat to the unsuspecting inhabitants of New York and Washington D.C. unifies them into an effective if not always efficient team. They discover the virus when five cases appear of what seems to be an acute and horrifying permutation of a rare neurological dysfunction that induces violent seizures and compulsive self-destruction by chewing on one's own flesh. The virus turns out to be a graft that could only have been produced by artificial means.

The search for the "mad scientist" with equipment capable of this sophisticated work takes weeks during which a handful of people have to live with the secret that a potential pandemic could literally explode in a local subway. The resolution, while in some ways satisfying, hardly dispels the uneasy implications which invite readers not only to serious reflection on our collective attitudes toward weapons research and development, but to activism.

View full annotation

Geek Love

Dunn, Katherine

Last Updated: Jan-24-1998
Annotated by:
Willms, Janice

Primary Category: Literature / Fiction

Genre: Novel

Summary:

Geek Love is the saga of a traveling carnival, the owners of which try to save it from financial failure by using ingested chemicals and toxins to create the birth of amazing freaks for the show. The outcome is a family that is both proud and vain about its specialness. The narrative unfolds the intricacies of greed and jealousy that tear the family asunder, resulting in the deaths of some members, the madness of others, and the escape of one.

It is Olympia, the hunchback albino dwarf, who lives on to tell the story of the Binewski clan. Central to the heyday of the carnival is Doc P, a physician of questionable credentials who performs bizarre operations in the traveling hospital that moves with the carnival. The story moves relentlessly toward a climax and denouement that is sufficiently unimaginable to be consistent with the cast of characters.

View full annotation

Brave New World

Huxley, Aldous

Last Updated: Jan-24-1998
Annotated by:
Coulehan, Jack

Primary Category: Literature / Fiction

Genre: Novel

Summary:

In the "brave new world" of 632 A. F. (After Ford), universal human happiness has been achieved. (Well, almost.) Control of reproduction, genetic engineering, conditioning--especially via repetitive messages delivered during sleep--and a perfect pleasure drug called "Soma" are the cornerstones of the new society. Reproduction has been removed from the womb and placed on the conveyor belt, where reproductive workers tinker with the embryos to produce various grades of human beings, ranging from the super-intelligent Alpha Pluses down to the dwarfed semi-moron Epsilons.

Each class is conditioned to love its type of work and its place in society; for example, Epsilons are supremely happy running elevators. Outside of their work, people spend their lives in constant pleasure. This involves consuming (continually buying new things, whether they need them or not), participating in elaborate sports, and free-floating sex. While uninhibited sex is universal and considered socially constructive, love, marriage, and parenthood are viewed as obscene.

The story concerns Bernard, an alpha whose programming is a bit off--he is discontented and desires to spend time alone just thinking or looking at the stars. At one point he takes Lenina on a vacation to the savage reservation in New Mexico. There he discovers John (the Savage), son of Linda who had visited the reservation more than 20 years previously and was accidentally left behind. When she discovered she was pregnant (the ultimate humiliation!), she had to remain among the savages. John returns to the Brave New World where he is feted as the Visiting Savage. However, he cannot adapt to this totally alien society and, ultimately, he takes his own life.

View full annotation

Pursuit of Excellence

Yount, Rena

Last Updated: Jan-28-1997
Annotated by:
Willms, Janice

Primary Category: Literature / Fiction

Genre: Short Story

Summary:

It is sometime in the future of genetic engineering, at the point at which, for a high enough price, one can buy physical and intellectual characteristics for one's fetus. This is the story of a young American couple of average means who have one "normal" son and are negotiating a supernorm status for their female fetus. The action centers around the stresses placed on the young family by the financial sacrifices required to engineer a daughter who would be able to compete in the growing population of engineered people. Husband and wife disagree increasingly, and ultimately the family breaks up over the wife's obsession with having a perfectly engineered child.

View full annotation