Summary:

Novelist Isabel Allende's daughter, Paula, died after entering into a coma following an acute attack of a porphyria disease. Allende was at her daughter's side in a hospital in Spain, where Paula was living with her husband, and later in Allende's home in California, where Paula spent the last months of her life.

When Paula first lost consciousness, Allende began writing for her an account of her illness, which soon grew into a memoir of Allende's own life: "Listen, Paula, I am going tell you a story, so that when you wake up you will not feel so lost" (p. 3), Allende begins. As Allende tells of her childhood, political and feminist awakenings, and her growth as a writer, she also watches Paula sink deeper and deeper into coma. She remains insistent, however, that Paula will recover, works in secret with a sympathetic physician to wean Paula from the respirator that breathes for her, then flies her back to California for rehabilitation.

In the end, though, she faces the reality that Paula will not recover, and, as she finishes telling Paula the story of her own life, she discovers that she has found the strength to let Paula go. Paula dies in a sunny room in Allende's house, surrounded by family and friends.

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This book is a series of essays about the illness experience. The author developed chronic fatigue syndrome (CFS) after a viral illness in 1988. Suddenly, this 41-year-old public policy analyst, who was also a successful writer and a competitive runner, was thrust into the world of severe disability. He developed subtle but extensive neurological deficits that affected his concentration and memory. For months he could hardly get out of bed. He discovered that not only was the cause of CFS unknown, many physicians did not even believe it was a "real" illness.

"Double Blind" tells the story of Skloot's participation in an ill-fated clinical trial of Ampligen, an experimental treatment for CFS. Other essays describe the author's experience with alternative medicine, including an intensive course of Ayurvedic "detoxification" ("Healing Powers") and a visit to Germany to encounter Mother Meera, an avatar of the Divine Mother ("Honeymooning With the Feminine Divine").

"Home Remedies" presents his comic experience with helpful calls and letters telling him how to get rid of the illness. Other essays deal with Skloot's learning to cope with chronic disability. A final section includes poems about the illness experience of several composers and artists (e.g. Carl Maria von Weber, George Gershwin, and Vincent van Gogh).

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This eight-part poem presents the wisdom of home remedies. The first voice tells the sick person to drink the juice of half a lime each day. "No virus can stand up / to a lime." The second voice explains the toxic effects of electromagnetic waves. Another tells him to submerge himself in garlic. Still another says to "visualize little men / in white overalls / scrubbing the lesions / from your brain." With regard to diet, one home remedy advises abstinence from bread, vinegar, dairy products, bread, corn, caffeine, alcohol, chocolate, vitamins, fruit, meat, fish, and fowl. In the end the only solution is to "embrace your illness . . . . "[133 lines]

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Determined not to like Ruth Thomas, Ann Stanley is immediately smitten by her charm and force of personality, and especially by her vitality--a vitality that too soon succumbs to breast cancer. As one of a cadre of women almost obsessively devoted to the care of a dying Ruth, Ann nurses Ruth through her final illness, until--in a move curiously like the decision of Charity (also dying of cancer) to keep Sid, her husband, sequestered from her final trip to the hospital, in Wallace Stegner's far superior novel, Crossing to Safety--Ruth flies to Florida to die at her brother's house.

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A witch doctor treated a man for trachoma with a caustic root, and the man went blind. Terrified and depressed, he sat in the doorway of his home for two years while "his wives ministered" to him. One night he went off on his own and "fell into a dry well and died upside down."

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The story begins with a philosophical discussion about how science (especially phrenology) understands human beings. It is the narrator's contention that science develops a priori. One first decides on the basic needs of humankind, then ascribes to certain organs the role of satisfying those needs. The narrator thinks this is backwards: "It would have been wiser, it would have been safer to classify . . . upon the basis of what man usually or occasionally did, and was always occasionally doing, rather than upon the basis of what we took for granted the Diety intended him to do."

One major trait scientists have overlooked is perversity. Men often do things for no better reason than that it will hurt themselves or others. The narrator then tells how he murdered a man and lived contentedly with the knowledge for many years until he was suddenly, perversely compelled to confess.

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The initial chapter in this novel, Of Mist, and Grass, and Sand (annotated separately), sets the stage for the quest of the young healer/heroine, "Snake," to find a replacement for the snake she had carelessly allowed to come to harm, in the course of caring for a seriously ill child. The remainder of this coming-of-age novel chronicles Snake's journey during her "proving year" (aka/residency training).

Over the course of this year, Snake continues to minister to the sick and encounters, among others, a patient who demands assistance in suicide, a patient who refuses treatment for a gangrenous leg, and a young girl who has been sexually abused (whom Snake eventually adopts and begins to apprentice). There are, as well, myriad lessons in humility, rigidity of thought, and ethnocentrism.

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A man called "The Counselor" is wandering the deserts, plains, and villages. He teaches scripture and rebuilds churches, like a monk, eating and sleeping very little. He attracts an odd group of followers--cripples, murderers, fanatical boys--and leads them to Canudos where they build a town and a glorious cathedral. The town is designed in imitation of Jerusalem. Many people flock to the site to see The Counselor; he heals them with a touch and washes them clean of sin.

The newly-installed conservative government is suspicious of Canudos, seeing it as a bastion of progressive sentiment. They resolve to attack the town and wipe it out. The Counselor, however, has long warned his followers that the Dog and his forces of evil will try to ruin their sanctuary.

When the small branch of the army sent to destroy what they think is a band of cripples and madmen arrives, they are slaughtered with all the vengeance of a holy war. The angered government sends a larger force and the town is eventually destroyed, but the few survivors insist that they saw The Counselor ascend to heaven, and so his reign lives on.

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Humphry Clinker is an epistolary novel, a collection of letters, that charts the adventures of a family group traveling through Britain. The head of the family is Matthew Bramble, a gouty old man, who is constantly writing his doctor with his complaints and visiting areas supposed to be good for his condition. He is accompanied by his niece, Lydia, who is in love with a poor man, Wilson. Her brother, an Oxford student, also comes along, as does Bramble's unwed sister, Tabitha. Tabitha's maid, Winifred Jenkins, accompanies her.

The group travels to Bath, London, Edinburgh, and the Scottish Highlands. Along the way, they meet Humphry Clinker, a dull-headed creature who becomes devoted to Matthew Bramble, even saving his life. He turns out to be Bramble's illegitimate son. Lydia's lover is discovered to be the son of a wealthy man who is Bramble's friend; they are finally happily married.

Tabitha marries Lismahago, an eccentric captain. Winifred Jenkins joins the festivities by marrying Clinker. Relieved of the feminine presence and bother in his life, Bramble recovers his health, writing to his doctor that from now on he will go hunting rather than write letters.

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Originally a three-part series in the New Yorker, this is an account of McPhee's six months of observing rural family doctors in Maine. It is both an engaging portrait of a kind of family practice increasingly rare in America, and implicitly an argument that those involved in professional medicine consider the tradeoffs in choosing between urban, high-tech, specialization and rural family practice where they know whole families in the context of community over time.

The narrative, based on interviews with physicians, some patients, and observations of clinical encounters, follows the daily routines and decision-making of several rural practitioners who consciously chose against the more lucrative, prestigious option of urban private practice, specialization, or academic medicine.

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